Abstract
We reported a peptide-based supramolecular hydrogel possessing a gel–sol phase transition triggered by H2O2.
Highlights
Due to the important significance of hydrogen peroxide (H2O2) in physiology, aging and disease in living organisms, tremendous effort has been devoted to develop H2O2 responsive materials for the detection of its over production or for controlled drug release
A supramolecular hydrogel based on peptide self-assembly was prepared through a heating–cooling process and its gel–sol phase transition could be triggered by the removal of thiazolidinone groups upon H2O2 oxidization
The excellent H2O2 responsive property of the supramolecular hydrogel was investigated by Liquid chromatography mass spectrometer (LC-MS), rheology and Transmission electron microscopy (TEM)
Summary
A novel H2O2 responsive supramolecular hydrogel for controllable drug release† Due to the important significance of hydrogen peroxide (H2O2) in physiology, aging and disease in living organisms, tremendous effort has been devoted to develop H2O2 responsive materials for the detection of its over production or for controlled drug release.
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