Abstract
Fluoroquinolone (FQ) resistance in Mycobacterium tuberculosis can be conferred by mutations in gyrA or gyrB gene. Recent studies suggest that amino acid substitutions in gyrB gene may also play a crucial role in resistance, but genetic studies of these mutations in M. tuberculosis are lacking.
Highlights
resistance in Mycobacterium tuberculosis can be conferred by mutations in gyrA or gyrB gene
Recent studies suggest that amino acid substitutions in gyrB gene may also play a crucial role in resistance
isolates of M.tuberculosis isolates were consecutively selected from routine TB laboratory
Summary
A novel gyrB gene mutation in fluoroquinolone resistant clinical isolates of Mycobacterium tuberculosis. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. 30 January - 1 February 2014
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