Abstract
AbstractConjugates of 2,4‐diamino sugars and uridine have been synthesized as galactosyltransferase inhibitors. The relationship between inhibitory activity and the chelation abilility of the hinge‐like diamino sugar towards a metal ion was studied by NMR spectroscopy. One of the conjugates exhibited a moderate inhibition that ranks between those of UDP and UMP probably through the chelation of the hinge‐like diamino sugar to MnII. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
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