Abstract

Meeting abstracts Systemic lupus erythematosus is a chronic, heterogeneous autoimmune disease, and there is no specific drug for its effective treatment, which may be because of its complexity on pathogenic mechanism. A multitude of studies of SLE in the last decade have accentuated a central role

Highlights

  • Systemic lupus erythematosus is a chronic, heterogeneous autoimmune disease, and there is no specific drug for its effective treatment, which may be because of its complexity on pathogenic mechanism

  • The Clinical Trials have proved the effectiveness of antibodies targeting multiple human IFN-a subtypes, especially the sifalimumab of AstraZeneca (IIb)

  • A novel fully human antibody that neutralizes multiple human IFN-a subtypes effectively was screened from fully synthetic human antibody library by Institute of Biotechnology, Academy of Military Medical Sciences

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Summary

Introduction

Systemic lupus erythematosus is a chronic, heterogeneous autoimmune disease, and there is no specific drug for its effective treatment, which may be because of its complexity on pathogenic mechanism. A novel fully human monoclonal antibody that neutralizes multiple human IFN-a subtypes effectively: a candidate therapy for SLE

Results
Conclusion

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