A novel fabricate of iron and nickel-introduced bimetallic MOFs for quickly catalytic degradation via the peroxymonosulfate, antibacterial efficiency, and cytotoxicity assay

Abstract

In this work, the Fe-doped Ni-MOFs was prepared by one-step solvothermal method. The ratio of Fe3+ dopant on the Fex/Ni1-x-MOFs was studied for characterization and catalytic degradation of enrofloxacin under the presence of peroxymonosulfate (PMS). The result shows the Fe0.25Ni0.75-MOFs has best catalytic activity for degradation (95.0%) at pH: 11 by 80 mg/L of catalyst dosage and 0.3 g/L PMS within 40 min. Moreover, Fe0.25Ni0.75-MOFs exhibits good reusability and stability in cycling experiments. The mechanism of catalysis process, and scavenging test showed that the •OH, and •SO4− in the degradation of enrofloxacin, and sulfate radical plays a major role. The antibacterial ability of prepared samples was studied versus Mycobacterium tuberculosis, and Helicobacter pylorio. The inhibition zone shows the best antibacterial activity of Fe-Ni-MOFs. The Fe-Ni-MOFs as a carrier to loading and releasing methotrexate (MTX) in a pH-sensitive system. The delivery efficiency of Fe-Ni-MOFs/MTX was investigated in vitro using melanoma cancer cell line. The novel Fe-Ni-MOFs displays the great potential for the antibiotics removal, bactericidal and drug delivery systems.