Abstract
Sucrose char sulfonic acid (SCSA) efficiently catalyzed the one-pot, three-component Mannich reaction of ketones, aromatic aldehydes and different amines in ethanol at 30°C and afforded the corresponding β-amino carbonyl compounds in good to excellent yields . This method provides a novel and improved modification of the three-component Mannich reaction in terms of mild reaction conditions , clean reaction profiles and a simple workup procedure.
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