A novel dopamine electrochemical sensor based on multiwall carbon nanotubes-cetyltrimethylammonium bromide/nitrogen doped ultra-thin carbon nanosheets composites modified glassy carbon electrode

Abstract

Dopamine (DA), as an important neurotransmitter, plays pivotal roles in addiction and some diseases. Fast and sensitive detection is of great value. Herein, a novel DA sensor based on multiwall carbon nanotubes-cetyltrimethylammonium bromide/zinc/cobalt @ nitrogen doped ultra-thin carbon nanosheets (MWCNTs-CTAB/Zn/Co@N-CNSs) was constructed. The 2D Zn/Co@N-CNSs was derived from the Zn/Co-ZIF precursor which was obtained by the simple salt stencil method. For the detection of DA, the MWCNTs-CTAB/Zn/Co@N-CNSs/GCE presented wide linear range (0.10 μM–12.0 μM) and low detection limit (LOD, 0.037 μM, (S/N = 3)).With the help of density function theory calculation results, the redox mechanism and electrochemical reaction sites of DA were further revealed. Besides, MWCNTs-CTAB/Zn/Co@N-CNSs/GCE achieved good recovery and accuracy in detecting DA in actual samples (bovine serum protein and human serum).