Abstract

Abstract The field of DNA computing emerged in 1994 after Adleman's paper was published. Henceforth, a few scholars solved some noted NP-complete problems in this way. And all these methods of DNA computing are based on conventional Watson-Click hydrogen bond of doublehelical DNA molecule. In this paper, we show that the triple-stranded DNA structure mediated by RecA protein can be used for solving computational problems. Sequence-specific recognition of double-stranded DNA by oligonucleotide-directed triple helix (triplex) formation is used to carry out the algorithm. We present procedure for the 3-vertex-colorability problems. In our proposed procedure, it is suggested that it is possible to solve more complicated problems with more variables by this model. *Supported by National Natural Science Foundation of China (Grant Nos. 60533010, 60373089, 60674106), Science Foundation of Shaanxi Bureau of Education (Grant No. 06JK202), Program for New Century Excellent Talents in University (No. NCET-05-0612) an...

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