Abstract
ABSTRACTCovalent capillary coatings of diazoresin (DR) and rapamycin (RAPA) were prepared by a layer-by-layer self-assembly. DR worked as the coupling agent. Under ultraviolet light, the corsslinking was carried out by covalent bonds between DR and RAPA. The covalent capillary coatings could suppress protein adsorption. The baseline separation of lysozyme (Lys), cytochrome c (Cyt-c), bovine serum albumin (BSA) and myoglobin (Mb) could be achieved within 17 minutes by using capillary electrophoresis (CE). The covalent capillary coatings exhibited good chemical stability and repeatability. In the synthesis, highly toxic moisture-sensitive silane has been replaced by DR. The method provides an environmentally friendly way to prepare the covalent capillary coating.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
