Abstract

Aim The objectives of this study were to develop a new bioactive composite resin containing silver/zinc oxide (Ag/ZnO) nanoparticles and investigate the effects on mechanical, cytotoxic, biocompatibility, and antimicrobial properties. Materials and Methods Disc-shaped specimens were prepared from composite with and without nanoparticles in separate culture media containing Streptococcus mutans, Lactobacillus, and Candida albicans. Bracket bonding evaluation was performed on composite without nanoparticles (O), composite containing ZnO (Z) nanoparticles, composite containing ZnO nanoparticles and silver ions (A&Z), and composite containing Ag/ZnO nanoparticles (AZ) synthesized using optical precipitation. Results Composite resin with nanoparticles (AZ, A&Z, and Z) showed significant antimicrobial properties (P < 0.05). The mean shear bond strength of A&Z composite resin (13.61 ± 0.73 MPa) was significantly less than that of conventional composite resin (19.03 ± 4.12 MPa) (P < 0.05). In addition, the mean shear bond strength of AZ composite resin (20.49 ± 1.03 MPa) was significantly higher than that of Z (16.35 ± 1.03 MPa) and A&Z composite resins. Conclusions Incorporation of ZnO nanoparticles and their compounds into orthodontic composite resins induced antibacterial properties against oral pathogens, and of all these nanoparticles, the AZ group exhibited the best antimicrobial activity and highest shear bond strength.

Highlights

  • Orthodontic treatment possesses many advantages for patients with functional and esthetic problems and results in the satisfaction of the majority of such patients. Such treatment might have complications for these patients, including demineralization, caries, and tooth discoloration around brackets and the bonded areas in the form of white spot lesions (WSL), which are considered a major challenge for clinicians and a major challenge factor for dissatisfaction of patients. is problem makes the patients susceptible to more widespread caries, especially in patients with poor oral hygiene

  • Dental materials, including endodontic sealers and adhesive cements, use this property of ZnO for bonding of fixed restorations. e results of a study by Tavassoli Hojati et al in relation to the effect of incorporating ZnO nanoparticles into flowable composite resins on the antibacterial, physical, and strength properties showed that an increase in the concentration of these nanoparticles resulted in a significant increase in the antibacterial properties of these composite resins [9]

  • Fluoride-releasing materials are appropriate for patients susceptible to caries, they are predominantly used in the dental office and there are limitations in relation to the number of times they can be used [14]

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Summary

Introduction

Orthodontic treatment possesses many advantages for patients with functional and esthetic problems and results in the satisfaction of the majority of such patients Such treatment might have complications for these patients, including demineralization, caries, and tooth discoloration around brackets and the bonded areas in the form of white spot lesions (WSL), which are considered a major challenge for clinicians and a major challenge factor for dissatisfaction of patients. Dental materials, including endodontic sealers and adhesive cements, use this property of ZnO for bonding of fixed restorations. e results of a study by Tavassoli Hojati et al in relation to the effect of incorporating ZnO nanoparticles into flowable composite resins on the antibacterial, physical, and strength properties showed that an increase in the concentration of these nanoparticles resulted in a significant increase in the antibacterial properties of these composite resins [9]

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