Abstract

A novel cyclohexenone, roxydienone (1), together with 13 known compounds (2–14), were isolated from the seeds of Trachyspermum roxburghianum. The structures of these compounds were established on the basis of their 1D and 2D NMR spectroscopic data. Compounds 1, 2, 7–9 and 14 showed cytotoxicity against NCI-H187 cell line while compounds 1 and 9 showed cytotoxicity against KB cell line. In addition, only compound 13 showed cytotoxicity against MCF-7 cell line.

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