Abstract
Probe-based confocal laser endomicroscopy (pCLE) offers real-time, cell-level imaging and holds promise for early cancer diagnosis. However, a large area surface scanning for image acquisition is needed to overcome the limitation of field-of-view. Obtaining high-quality images during scanning requires maintaining a stable contact distance between the tissue and probe. This work presents a novel contact optimization algorithm to acquire high-quality pCLE images. The contact optimization algorithm, based on swarm intelligence of whale optimization algorithm, is designed to optimize the probe position, according to the quality of the image acquired by probe. An accurate image quality assessment of total co-occurrence entropy is introduced to evaluate the pCLE image quality. The algorithm aims to maintain a consistent probe-tissue contact, resulting in high-quality images acquisition. Scanning experiments on sponge, ex vivo swine skin tissue and stomach tissue demonstrate the effectiveness of the contact optimization algorithm. Scanning results of the sponge with three different trajectories (spiral trajectory, circle trajectory, and raster trajectory) reveal high-quality mosaics with clear details in every part of the image and no blurred sections. The contact optimization algorithm successfully identifies the optimal distance between probe and tissue, improving the quality of pCLE images. Experimental results confirm the high potential of this method in endomicroscopic surface scanning.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: International journal of computer assisted radiology and surgery
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.