Abstract

A bipolar pulse has been proved to be more advanced in the treatment of tumor because of the elimination of muscle contractions and the effect for ablating nonuniform tissue. In this paper, a new type of modular bipolar pulsed-power generator based on Marx generator with double power charging is proposed. The concept of this generator is charging the two series of capacitors in parallel by two power sources, respectively, and then connecting the capacitors in series through solid-state switches with different control strategies. Utilizing a number of fast solid-state switches, the capacitors can be connected in series with different polarities, so that a positive or negative polarity pulse will be delivered to the load. The simulated models of this generator have been investigated in a PSPICE platform, and a laboratory prototype has been implemented in a laboratory. The simulation and test results verify the operation of the proposed topology in different switching modes. The development of this pulse generator can provide the hardware foundation for the research on biological effect without muscle contraction when the tumors are applied with bipolar pulse electric field.

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