Abstract
Abnormal levels of endogenous sulfur dioxide in organisms will cause cardiovascular, respiratory and neurological diseases. Therefore, the development of an effective detecting method for real-time, quantitative detection of sulfur dioxide derivatives in organisms is of great importance in physiological and pathological aspects. In this work, a red-emitting SO2 fluorescent probe based on benzopyrylium derivatives were designed and synthesized to specifically detect SO2 derivatives by nucleophilic addition of unsaturated carbon-carbon double bonds. The probe is characterized with rapid response, “naked eye” visualization, broad detection range and high sensitivity (8.1 μM) for SO2 derivatives. In addition, it has been applied to track the dynamic, real-time, visual detection of exogenous and endogenous SO2 in cells, and imaging of exogenous SO2 derivatives in zebrafish.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
