Abstract

A new chiral calix[4]arene-based organocatalyst3bearing bis-squaramide moieties was designed and synthesized fromp-tert-butylcalix[4]arene. This bifunctional organocatalyst was used in the enantioselective conjugate addition of acetyl acetone to β-nitrostyrenes. The corresponding adducts were obtained in good to excellent yields with high enantioselectivities.

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