A Novel Bisoxazoline‐Imidazolium Salt in Ytterbium‐Catalyzed Asymmetric Reduction of Ketone

Abstract

Chiral N‐heterocyclic carbene (NHC), a privileged ligand for transition metals, has had a profound impact on organometallic chemistry. The monodentate and bidentate chiral carbenes have been developed significantly, while the tridentate ones have been less exploited. Herein, we designed and synthesized a new bisoxazoline‐imidazolium salt as a carbene precursor, which owns three chelating sites and two kinds of chiral information centers. A preliminary investigation on the asymmetric ketone reduction was also studied.