A novel array-type microdroplet parallel-generation device.

Abstract

In this study, the innovative design of a new array microdroplet parallel-generation device is proposed based on the principle of fluid inertial force using a capillary glass needle. The entire device used an electromagnetic actuator as the power source. It was designed as a 9-channel parallel array of glass needles. All glass needles feed independently, allowing different solutions to be sprayed simultaneously while effectively avoiding cross-contamination. We achieved non-contact parallel precision dispensing of nanoliter-sized microdroplet arrays using a relatively simple method. In this study, we first investigated the homogeneity of the generated droplet arrays and the stability of the device over long periods of operation. Then, the influence of the driving-voltage amplitude of the electromagnet and nozzle diameter on microdroplet generation was analyzed. Finally, a prediction model for the droplet size was developed using regression analysis to investigate the on-demand generation of droplets. In summary, the device designed in this study had a novel design, low cost, and modular assembly. It has excellent potential for applications in high precision and low-volume microdroplet-array generation.