Abstract
Aptamers as new modes of detection have strong affinity and specificity for targets. A novel sensor was developed by constructing a composite system of specific aptamers and reduced graphene oxide (rGO)/graphitic carbon nitride (g-C3N4) (GCN) for detecting the cadmium cation. Attributed to the incorporation of rGO and aptamers with designed terminal groups as well as the delicate bonding of aptamers with g-C3N4, this electrochemical biosensor exhibited good sensitivity, specificity, reproducibility, and stability for Cd2+ detection. The linear calibration curves range from 1 nM to 1 μM and from 1 μM to 1 mM, and the limit of detection (LOD) was calculated to be 0.337 nM. The practical application of the proposed method was also verified in the real sample.
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