A novel and simple deep eutectic solvent based liquid phase microextraction method for rhodamine B in cosmetic products and water samples prior to its spectrophotometric determination

Abstract

A novel and green deep eutectic solvent based liquid phase microextraction (DES-LPME) methodology has been proposed for the assessment of rhodamine B from cosmetic products and water samples. A deep eutectic solvent (DES) consist of tetrabutyl ammonium chloride-decanoic acid (1:2) as extraction solvent and tetrahydrofuran as emulsification agent were used for the microextraction of rhodamine B. The quantitative recoveries were achieved at pH 3 by using 0.3 mL of DES and 0.3 mL of THF. The rhodamine B concentration in last volume was analyzed by mirco-cuvette UV-VIS spectrophotometer at 550 nm. The limit of detection (LOD), limit of quantification (LOQ), preconcentration factor (PF) and relative standard deviation (RSD %) were found as 2.2 μg L−1, 7.3 μg L−1, 25 and 2.3%, respectively. Accuracy and validity of the developed method was verified by addition-recovery studies for water and cosmetic samples.