Abstract
Abstract Ketene dithioacetals bearing an alkoxycarbonyl group at 2-position are effectively reduced by two equimolar amounts of dimethylcuprate derived from methyllithium and cuprous cyanide to yield the corresponding functionalized vinylcopper species. These organocopper species are efficiently trapped by carbon electrophiles. Formal substitution reactions of a methylthio group in ketene dithioacetals by electrophiles can be attained by one-pot operation. Synthesis of β-thiobutenolides was also achieved.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
