Abstract
Actaplanin, a complex of glycopeptide antibiotics produced by Actinoplanes missouriensis, was investigated as a performance enhancer when incorporated in the diet of lactating dairy cows at the rate of 960 mglday. In a trial with autumn-calving cows over two successive lactations, the milk yield of animals given diets incorporating Actaplanin (no. = 132 lactations) showed only a small (proportionately +0·038), nonsignificant increase in milk yield over the controls (no. = 121 lactations). Overall, there were no significant differences in milk composition, cow body weight or condition score changes, mastitis cell counts or in the majority of blood metabolites.
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