Abstract
The V54L missense mutation within the DECR1 gene, which encodes a mitochondrial 2,4- dienoylCoA reductase, was investigated to determine whether this polymorphism is associated with growth rate (daily gains), meat content and selection index in Polish Landrace boars kept under uniform feeding and environmental conditions (one herd). The genotype of 334 boars was determined by PCRRFLP, identifying 112, 162, and 60 boars bearing genotypes CC, CG and GG, respectively. Statistical analysis was carried out by the General Linear Model (GLM) procedure, including fi xed effects of DECR1 genotype, sire, and birth season. Signifi cant differences (P<0.01) between boars with CC and GG genotypes were found. Boars with genotype CC showed the highest daily gains (860.7 g ± 46.3), in comparison with boars bearing the GG genotype (841.7 g ± 53.6). The current fi ndings support the hypothesis that DECR1 V54L polymorphism is a promising marker of growth rate in pigs.
Highlights
Improving meat performance is one of the most challenging tasks in commercial pig breeding
The key role of DECR1 in fat and protein metabolism encouraged us to investigate whether this polymorphism is associated with growth rate, meat content and selection index in Polish Landrace boars
When validating a set of pre-selected candidate SNPs addressed for diverse application in pig breeding (SNiPORK chip; Kaminski et al, 2008) we noted that DECR1 had balanced genotype and/allele frequency, predisposing this SNP for wider association studies
Summary
Improving meat performance is one of the most challenging tasks in commercial pig breeding. Searching for new functional DNA polymorphisms and testing their associations with meat performance traits in pigs has been the purpose of many studies during last two decades (reviewed by Brym and Kaminski, 2006). Among 88 SNPs analysed by our group, the missense mutation V54L within the DECR1 gene encoding a mitochondrial 2,4 dienoyl CoA reductase (Clop et al, 2002) showed balanced genotype and allele distribution in major commercial porcine breeds (Kaminski et al, 2008), giving a chance for reliable association studies. The key role of DECR1 in fat and protein metabolism encouraged us to investigate whether this polymorphism is associated with growth rate (daily gains), meat content and selection index in Polish Landrace boars
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
