Abstract
A note on arterial to venous oxygen saturation as reference for NIRS-determined frontal lobe oxygen saturation in healthy humans
Highlights
Near infrared spectroscopy (NIRS) offers non-invasive assessment of oxygenation within the human brain (ScO2) by appreciating the different absorption of near infrared light by hemoglobin and oxyhemoglobin (Jobsis, 1977)
The lowest root mean square error (RMSE) was observed for a 75% arterial and 25% jugular venous blood contribution to ScO2(RMSE = 2.70; R2 = 0.644; P < 0.0001; Figure 1A)
When ScO2 was compared with the calibration ratio, the mean difference was zero in 2.9% of the blood samples, whereas it was 10.5% when ScapO2 was used as reference (Figure 1B)
Summary
Near infrared spectroscopy (NIRS) offers non-invasive assessment of oxygenation within the human brain (ScO2) by appreciating the different absorption of near infrared light by hemoglobin and oxyhemoglobin (Jobsis, 1977). By linear regression the contribution from arterial and jugular blood to ScO2 was estimated and Rsquared (R2) and root mean square error (RMSE) between ScO2 and the arterial fraction in the reference saturation were calculated (SAS Institute Inc., Cary, NC). All reference saturations were calculated, e.g., ScapO2 = 0.50 · SaO2 + 0.50 · SjO2.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
