Abstract
Tooth agenesis is a condition where teeth are missing due to developmental failure. It is often seen in one-quarter of general population making it the most common of human developmental anomalies and it may or may not be associated with syndromes. Oligodontia is a rare hereditary or developmental anomaly showing absence of 6 or more teeth with the incidence varying from 0.08% to 0.16%. The genes expressed in embryonic tissues associated with non-syndromic tooth agenesis are found to be MSX1 and PAX9 genes. These genes play a key role in tooth development, where PAX9 and MSX1 are responsible for odontogenesis in multicuspids and incisors respectively.
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