Abstract

SR 48968, N-Methyl-N-[4-(4-acetamido-4-phenylpiperidinyl)-2S-(3,4-dichlorophenyl) butyl]benzamide is a potent and selective non-peptidic antagonist of the NK 2 receptor. photoactivatable analogue containing a diazirine moiety also binds with high affinity. This compound is potentially useful for identifying residues at the antagonist binding site of the NK 2 receptor.

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