Abstract
There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be further clarified. In the present perspective, we collected commentaries and descriptions about clinical and translational medicine from some members of Clinical and Translational Medicine editorial board to stimulate the discussion and help the understanding better.
Highlights
There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be further clarified
The interest in personalized medicines results from understanding the molecular biology of diseases
I have been involved in large such non-small cell lung cancer (NSCLC) in several studies in Asia, and the outcome and impact has been overwhelming
Summary
There is growing evidence to the importance of translational science and medicine in the improvement of patient outcome, even though the definitions of translational science, translational medicine, and clinical and translational medicine need to be further clarified. John Hutton (Professor of Pediatrics, Vice President and Director, Biomedical Informatics, Cincinnati Children's Hospital Medical Center, University of Cincinnati) describes that a perfectly reasonable, “official” definition of translational research should be “Translational research transforms scientific discoveries arising from laboratory, clinical or population studies into new clinical tools and applications that improve human health by reducing disease incidence, morbidity and mortality” modified from “Transforming Translation – Harnessing Discovery for Patient and Public Benefit” (Report of the Translational Research Working Group of the National Cancer Advisory Board, US NIH, 2007).
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