Abstract

AbstractThe reaction between ethyl 3‐bromopyruvate and p‐substituted anilines was found to involve the unexpected participation of acetone (solvent) forming N‐aryl‐5‐methyl‐pyrrole‐3‐carboxylates. The influence of p‐substituents of aniline and the feasibility with other ketones were studied. N‐aryl‐indole‐3‐carboxylate (17) was synthesized successfully with this method. The unique character of p‐methoxy‐aniline in this reaction was discussed.

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