Abstract

A new triterpene glycoside, leucospilotaside A, along with a known saponin, isolated from sea cucumber Holothuria leucospilota, and its structure was elucidated as 3β- O-[4- O-sodiumsulfate-β- d-quinovopyranosyl-(1 → 2)-β- d-xylopyranosyl]-holosta-22-ketone-9-en-17α,25α-diol ( 1) by extensive spectroscopic analysis and chemical methods. Leucospilotaside A ( 1) has a ketone carbonyl group (22) in the aglycon side chain.

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