Abstract
A new transmission map of HIV-1 CRF07_BC in China: analysis of sequences from 12 provinces over a decade
Highlights
HIV-1 CRF07_BC descended from subtypes B’ and C represents one of the most prevalent HIV-1 strains in Asia and has been devastating in IDUs for more than a decade in China
Almost all Chinese literatures on early HIV-1 epidemic history are reviewed to confirm the results of sequences analysis
After the initial epidemic regions, including Guangxi, Xinjiang and Sichuan, served as secondary epicenters for further spreading, triggered further transmission into Gansu, Ningxia, Qinghai, Beijing and Hunan during 19992001. These analyzed results are in accordance with early epidemic investigations of HIV-1
Summary
HIV-1 CRF07_BC descended from subtypes B’ and C represents one of the most prevalent HIV-1 strains in Asia and has been devastating in IDUs for more than a decade in China. Several groups made their effort to address its origin and migration pattern, and had generated several enlightening conclusions, the limited available sequences may have restrained the precise depiction of global migration pattern of CRF07_BC. Epidemic evidences and sequences analysis was combined to investigate the transmission linkages among 12 CRF07_BC epidemic regions in China and their tMRCA(time of most recently common ancestor)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
