A new therapy (MP29‐02*) provides effective relief from all individual nasal and ocular symptoms of seasonal allergic rhinitis

Abstract

MP29-02* reduced nasal congestion by -1.24 vs -0.86 for FP (Diff: -0.39; 95% CI -0.65, -0.13; p=0.0034), -0.75 for AZE (Diff: -0.49; 95% CI: -0.74, -0.24; p=0.0001) and -0.54 for placebo (Diff: -0.70; 95% CI -0.95, -0.45; p<0.0001), with a relative difference of 54% to FP and 70% to AZE. A similar and significant superiority of MP29-02* over FP and AZE was observed for nasal itching (44% to FP, 56% to AZE), rhinorrhoea (32% to FP; 65% to AZE) and sneezing (49% to FP; 61% to AZE). The most bothersome ocular symptom of itching was reduced by -1.23 by MP29-02* vs -0.70 for FP (Diff: -0.53; 95% CI: -0.79, -0.26; p=0.0001), -0.88 for AZE (Diff: -0.35; 95% CI -0.63, -0.08; p=0.0127) and -0.44 for placebo (Diff: -0.79, 95% CI -1.04, -0.54; p<0.0001) with a relative difference of 67% to FP and 44% to AZE. The relative differences to FP and AZE respectively were 51% and 25% for ocular watering, and 53% and 40% for ocular redness.