Abstract
A new theoretical index of the chemical reactivity of sites within macromolecules is developed, which combines both steric and electrostatic factors. It is applied to the study of yeast tRNAPhe and the results obtained are compared with known experimental reactivities. A comparison indicates the superiority of the new index over the sole use of the surface accessibility.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have