Abstract
Allosteric process isn’t new, but recently it has acquired even greater application prominence. In a recent review Exploring allostery’s advantages on this phenomenon, [1] (C&EN Chicago) says “drug hunters are increasingly turning their attention to allosteric sites – the often tough-to-find regulatory pockets. A crop of allostery-focused biotech has emerged to illuminate proteins’ hidden sites with a combination of better experimental and computational tools”. By a theoretical point of view, moreover, the concept of allostery can also assume a larger definition.
Highlights
Allosteric process isn’t new, but recently it has acquired even greater application prominence
B) it is important to explain how it is possible a selectivity between two distant sites of the macromolecule in a very complex system with a very large number of states. Both topics have been considered by us with the help of a quantum approach. This is the first time that allostery has been studied by Quantum Mechanics (QM)
Two are the reasons why we have decided to apply QM to this phenomenon. It is well-known that the correct mechanical theory for studying the molecular world is QM; at the moment, only Classical Mechanics theory has been applied to the study of allostery from a mechanical point of view
Summary
Allosteric process isn’t new, but recently it has acquired even greater application prominence. Allostery can be defined as the alteration of a property in its active site due to a perturbation generated in its sensor (allosteric) site. This is the first time that allostery has been studied by Quantum Mechanics (QM).
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: American Journal of Biomedical Science & Research
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
