Abstract
IntroductionAlthough the traditional bilateral surgical approach to treat hiatal hernia (HH) with gastroesophageal reflux disease (GERD) can provide local protection of the vagus nerve, the integrity of the entire vagus nerve cannot be evaluated. Therefore, we developed and described the total left-side surgical approach (TLSA), which theoretically reduces injury to the vagus nerve, and described the detailed surgical procedure.MethodsInitially, we performed a cadaver study to explore the characteristics of the vagus nerve. Then, we prospectively evaluated the TLSA in 5 patients with HH and GERD between June 2020 and September 2020. Demographic characteristics, surgical parameters, perioperative outcomes, and follow-up findings were analyzed.ResultsThe TLSA was successfully used in five patients (40–64 years old), and no major complications were noted. The median total operative time was 114 min, median blood loss was 50 mL, and median postoperative hospital stay was 3.8 days. Gastrointestinal function recovered within 4 days of surgery in all the patients. The 6-month follow-up gastroscopy examination showed well-established gastroesophageal flap valves. Compared with the baseline results, the 6-month follow-up results showed lower values for the total GerdQ score (12.4 vs. 6.2) and the total esophageal acid exposure time (3.48% vs. 0.38%). Based on the European Organization for Research and Treatment of Cancer quality of life questionnaire-stomach module 52 results, the incidence of dysphagia and flatulence decreased over time after the TLSA.ConclusionsThe TLSA provides a clear and broad surgical field, less trauma, and rapid recovery; moreover, it is technically simple. Although our results suggest that the TLSA provides safety and short-term efficacy and is feasible for patients with HH and GERD, long-term results from a larger clinical trial are needed to validate these findings.Trial registration ChiCTR2000034028, registration date is June 21, 2020. The study was registered prospectively
Highlights
The traditional bilateral surgical approach to treat hiatal hernia (HH) with gastroesophageal reflux disease (GERD) can provide local protection of the vagus nerve, the integrity of the entire vagus nerve cannot be evaluated
The current primary treatment for HH with GERD involves the use of the traditional bilateral surgical approach (TBSA) to perform laparoscopic HH repair and Nissen fundoplication [6]
Inclusion criteria The inclusion criteria are listed as follows which we described in previously work [9]. (1) Patients must have HH with GERD that is diagnosed via gastroscopy, high-resolution esophageal manometry, and 24-h esophageal pH monitoring
Summary
The traditional bilateral surgical approach to treat hiatal hernia (HH) with gastroesophageal reflux disease (GERD) can provide local protection of the vagus nerve, the integrity of the entire vagus nerve cannot be evaluated. The current primary treatment for HH with GERD involves the use of the traditional bilateral surgical approach (TBSA) to perform laparoscopic HH repair and Nissen fundoplication [6]. While this procedure can provide local protection of the vagus nerve, the integrity of the entire vagus nerve cannot be evaluated. These injuries can affect the patient’s reflux symptoms and quality of life [7, 8]
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