Abstract
AbstractNatural polysaccharides supported tetrabutylammonium fluoride (TBAF) complexes are prepared and found to be highly stable and selective fluoride source for well‐renowned nucleophilic (SN2 type) fluorination reactions for the first time. Bacterial cellulose, plant cellulose, pectin, and starch derived TBAF complexes are synthesized, characterized (using SEM, TEM, and NMR techniques) and studied for their stability and reactivity. Heterogeneous bacterial cellulose‐TBAF complex (NBu4(Bac‐cell‐OH)F) 1 was found to be highly stable and non‐hygroscopic among all complexes, which gave high yields of fluorinated products in multi‐gram scale in shorter reaction time. The primarily developed batch protocol was extended to solid‐solid continuous flow reaction using an in‐house built screw reactor, which furnished products in a few seconds of residence time (tR=20–25 sec) and excellent yields.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
