A NEW STRATEGIES: ANTIBIOTIC CIRCUMSTANCES FOR RATIONAL DRUG USE AGAINST CLINICAL AEROMONAS HYDROPHILA AND BACTERIAL PROPERTIES OF THIS BACTERIA ON DIFFERENT AGARS

Abstract

Antibiotic resistance of A. hydrophila was once again observed on different agars. Random antibiotics drug treatment of diseases causes development resistance. Thus, we have faced post-antibiotic era in which our ability to challenge bacteria has diminished and the need for new strategies to deal with disease has increased. A. hydrophila ATCC reference strain, which causes the fatal Motil Aeromonas Septicemia (MAS) Disease in fish, was used in the study Colony structure of A. hydrophila formed on MacConkey (MAC), Aeromonas Isolation Base Agar (AIBA), Congo Red Agar (CRA) and Blood Agar (BA) were examined. The antibiotic susceptibility was determined by using the Kirby-Bauer method Mueller–Hinton Agar, MAC, AIBA and CRA agar plates. A. hydrophila was found sensitive to ciprofloxacin, enrofloxacin, gentamicin, sulphamethoxazole/trimethoprim, and resistant to penicillin G and oxacillin. The important difference was obtained as resistant to enrofloxacin on MAC. Multiple antibiotic resistance index (MARI) of A. hydrophila was determined as 0.33 in MHA and 0.5 in MAC. This difference was due to the antibiotic enroflaxin, and its appearance in this study, where a different new approach was tried for the first time, also added originality to the subject. This status may be related to an acquired plasmid. It is important to try to see resistance of A. hydrophila by using different agars while innovations such as the AntibiogramJ program are being tried to be added to antibiotic literature.