A new stereocontrolled access to angularly disubstituted cis-decalins via tandem radical ring expansion and cyclization

Abstract

The complete stereocontrolled access to angularly disubstituted cis-decalins based on the tandem radical ring expansion and cyclization process of α-iodomethylcyclopentanones 1 and 6 is described. The compounds 2–5 and 7–13 thus prepared could be versatile intermediates for the synthesis of biologically important compounds.