A new sesquiterpenoid juvenile hormone III from the stems of Cananga latifolia

Abstract

A new juvenile hormone III, canangalia I (1), along with six known juvenile hormone III analogues (2–7), was isolated from the methanolic extract of Cananga latifolia stems. All structures were elucidated using spectroscopic data and compared with data from previous literature. Canangalia I (1) was found to be cytotoxic against human cervical adenocarcinoma (HeLa) cells with an IC50 value of 35.00 ± 2.15 µg/ml after 72 h, but was not toxic to Vero cells.