Abstract
Column chromatographic separation of a MeOH extract of the aerial parts of Saussurea triangulata led to the isolation of a new sesquiterpene glycoside 6, together with three quinic acid derivatives, two phenolics, two sesquiterpene glycosides and two flavonoids. The new compound 6 was identified as amarantholidol A glycoside by spectroscopic and chemical methods.
Highlights
In a continuation of our study on biologically active compounds from Korean Compositae plants [1,2], the phytochemical constituents of the aerial parts of Saussurea triangulata were investigated
S. triangulata is widely distributed in Korea, and has been used in Korean folk medicine for the treatment of inflammation, hypertension and hepatitis [3]
By comparison of their spectral data (1H, 13C-NMR and MS) with that reported in the literature, compounds 1-5 and 7-10 were identified as 3-caffeoylquinic acid (1) [4], methyl 4-caffeoylquinic acid (2) [5], methyl 5-caffeoylquinic acid (3) [6], 4-hydroxybenzoic acid (4) [7], syringin (5) [8], amarantholidoside II (7) [9], (-)-oplopan-4-one-10-α-O-β-D-glucoside (8) [10], 7,4'-di-O-methylapigenin 5-O-α-D-xylopyranosyl-(1→6)-β-D-glucopyranoside (9) [11,12] and 7-O-methylapigenin 5O-α-D-xylopyranosyl-(1→6)-β-D-glucopyranoside (10), respectively [11]
Summary
In a continuation of our study on biologically active compounds from Korean Compositae plants [1,2], the phytochemical constituents of the aerial parts of Saussurea triangulata were investigated. Purification of the MeOH extract of the aerial parts from S. triangulata by column chromatography yielded a new compound 6, together with nine known compounds: three quinic acid derivatives 1 - 3, two phenolics 4 and 5, two sesquiterpene glycosides 7 and 8, and two flavonoids 9 and 10 (Figure 1).
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