Abstract
l-Cysteine (Cys) plays a vital part in the food industry and biological processes. Herein, a novel ratiometric fluorescent probe NFA with aggregation-induced emission (AIE) property was developed to discriminate Cys from Hcy and GSH. The probe showed a ratiometric fluorescence response to Cys with the emission wavelength shifted from 450 nm to 495 nm. Probe NFA possessed good advantages in the detection of Cys including wide linear range (0–100 μM), low detection limit (0.21 μM), and rapid response time (within 2 min). Compared with previous reports, this is the first ratiometric probe that achieves the quantitative detection of Cys in different food samples in real-time (cabbage, bamboo shoots, lotus root, garlic, apple, pear, milk powder, and liquid milk). Moreover, NFA is successfully applied for ratiometric image endogenous and exogenous Cys in HeLa cells and zebrafish which demonstrated its practical biological application.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
