Abstract
The aim of this study consisted in the development of a rapid and reliable high performance liquid chromatography (HPLC) method for resveratrol identification and assay in food supplements, trying to offer a robust, direct and convenient solution. By this method, several supplements with varying resveratrol content, between 103 and 119% of the stated amount per dosage form, were analyzed.
Highlights
The aim of this study consisted in the development of a rapid and reliable high performance liquid chromatography (HPLC) method for resveratrol identification and assay in food supplements, trying to offer a robust, direct and convenient solution
Resveratrol can be used on one hand in manufacturing of food supplements and on the other hand, due to its antioxidant effects, in the manufacturing of cosmetic products, industry which increasingly focuses on the development of active cosmetics [9, 10]
The supplements analyzed were coded as follows: -PB001 - is presented as hard gelatin capsules containing 50 mg resveratrol/cps
Summary
The aim of this study consisted in the development of a rapid and reliable high performance liquid chromatography (HPLC) method for resveratrol identification and assay in food supplements, trying to offer a robust, direct and convenient solution. Resveratrol has been the subject of intense interest in recent years due to a range of unique anti-aging properties.These include cardiovascular benefits via increased nitric oxide production, down-regulation of vasoactive peptides, lowered levels of oxidized low-density lipoprotein, and cyclooxygenase inhibition; possible benefits on Alzheimer disease by breakdown of betaamyloid and direct effects on neural tissues; phytohormonal actions; anticancer properties [6]. Resveratrol can be used on one hand in manufacturing of food supplements and on the other hand, due to its antioxidant effects, in the manufacturing of cosmetic products, industry which increasingly focuses on the development of active cosmetics [9, 10]. Resveratrol (and other antioxidants) is combined with various plant extracts containing polyphenols in order to enhance healthpromoting effects [12], including antioxidative properties [13].
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