Abstract
A new phenolic glycoside 1, together with its enantiomer (2), was isolated from the ethanolic extract of Viburnum melanocarpum P. S. Hsu fruits by repeated column chromatography. Its structure was identified as (7R,8S)-guaiacylglycerol 4-O-β-D-(6-O-vanilloyl)glucopyranoside (1) by spectroscopic data (1H NMR, 13C NMR, HSQC, HMBC, and ORD) and chemical methods. In the intestinal α-glucosidase inhibitory activity test, compound 1 exhibited potent inhibitory activity with IC50 value of 10.04 μM in comparison with the positive control acarbose (IC50 16.37 μM).
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