Abstract
Bioanalysis was of no importance to drug discovery for 65 years. Today, it seems almost impossible that a drug could be discovered, developed and marketed without extensive bioanalysis. This brief editorial looks back at drug discovery practices and tries to provide a logical sequence of thinking and events that led to today. The author's belief is that the ingenuity and skills of bioanalytical scientists will be tested to the utmost in the present and future phase. Although simplistic, the author has divided drug discovery into three phases: PD, PK and PK/PD. The PD phase of drug discovery
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