Abstract
We have proposed and realised a new synthetic approach for the preparation of liquid crystalline dicyclohexyl derivatives. Recently discovered reaction of Grignard reagents with esters leading to 1-substituted cyclopropanoles in the presence of tetraisopropoxytitanium was used as a key stage. Starting from ethyl trans-4-alkylcyclohexancarboxylates the corresponding 6-(4-alkylcyclohexyl)-3-alkylcyclohex-2-en-1-ones have been prepared. Their catalytic hydrogenation in the base media gave mainly saturated trans,trans-ketones which are liquid crystalline and can be used also as a promising intermediate products for the preparation of different kinds of other LC compounds containing bicyclohexane moiety.
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