Abstract
Background Corticosteroids are active agents, which are especially applicated orally in the dermatological emergency medicine. Due to German anaphylaxis guidelines patients emergency kit must contain a corticosteroid with a Prednisolone-equivalent of at least 100 mg. Due to different reasons, a liquid corticosteroid is to be recommended. At the present time, there is no comparable liquid remedy available. The alternative is intravenously administered prednisolone. Due to this reason, a new formula is created by a research group of pharmacologists and dermatologists. They are working close to the Pharmaceutical Laboratory of the New Prescription Formulatory (NRF) in Germany, which is developing new formulations, also the Prednisolone formula. The new formula contains a Prednisolone-equivalent up to 500 milligrams per 100 milliliters liquid agent.
Highlights
Corticosteroids are active agents, which are especially applicated orally in the dermatological emergency medicine
A new formula is created by a research group of pharmacologists and dermatologists
We studied 60 patients, who came on an emergency basis to our university hospital with severe acute or chronic spontaneous urticaria and/or angioedema, half of them including throat swallowing
Summary
Corticosteroids are active agents, which are especially applicated orally in the dermatological emergency medicine. Due to German anaphylaxis guidelines patients emergency kit must contain a corticosteroid with a Prednisolone-equivalent of at least 100 mg. A liquid corticosteroid is to be recommended. Due to this reason, a new formula is created by a research group of pharmacologists and dermatologists. A new formula is created by a research group of pharmacologists and dermatologists They are working close to the Pharmaceutical Laboratory of the New Prescription Formulatory (NRF) in Germany, which is developing new formulations, the Prednisolone formula. The new formula contains a Prednisolone-equivalent up to 500 milligrams per 100 milliliters liquid agent
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