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Abstract
The “speedometer cable” model of DNA replication is a widely used hypothesis. However, it has never been proven. On the contrary, experimental facts have been accumulating which make this model less and less likely. Particularly, the postulated rotation of the entire replicating molecule is highly improbable when the bacterial chromosome is considered. We have suggested another hypothesis which does not involve the rotation of the molecule and seems to be consistent with known experimental observations. It consists of enzymatic disassembling of one strand which is then transferred piece by piece and rebuilt in its original shape as a part of a daughter molecule. The other strand remains available for RNA replication.
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