Abstract

On the basis of recent electron microscopic observations by Sjostrand and Barajas23 and available biochemical information, a model describing the molecular structure of mitochondrial membranes was designed. In addition to accounting for the structural features of those membranes as revealed by electron microscopy, this model also pays due attention to the fact that a large number of enzymes and electron carrier molecules are basic components of the membranes. The fundamental justification for such a model which is to assist in an understanding of membrane function is satisfied as far as general principles are concerned. The other justification of such a model concept is to allow predictions regarding additional properties of the membrane. Such predictions have made it possible to design future experiments which can add further information regarding the molecular structure of cellular membranes.

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