Abstract

ABSTRACT The one-pot reaction of halo-heterocycle, (R)-4-hydroxyphenoxy propionic acid and an alcohol, amine or sulfonamide is described as an efficient method for the synthesis of aryloxyphenoxy propionate hrerbicides by using 2,4,6-trichloro-1,3,5-triazine in the presence of ( n - Bu) 4 NI, as a homogeneous catalyst under mild conditions. The present procedure offers several advantages, such as good yields, short reaction times and easy workup. Keywords: One-pot reaction, Catalyst, Aryloxyphenoxy propionate, Cyanuric chloride e-mail: adadras@guilan.ac.ir INTRODUCTION The one-pot reaction is known as a reaction in which three or more easily accessible compounds are combined in a single reaction vessel. 1-6 One-pot reactions increase the efficiency of reactants by combing several operational steps without isolation of intermediates or changing the reaction conditions. Speed, diversity, efficiency and environmental amiability are some of the major advantages of these reactions. They have emerged as valuable tools for the preparation of structurally diverse chemical libraries of drug-like heterocyclic compounds.

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