Abstract
A new method for construction ion-selective electrode (ISE) by heating reaction of methyl orange with ammonium reineckate using PVC as plasticizer for determination methyl orange and determination Amitriptyline Hydrochloried drug by formation ion-pair on electrode surface . The characteristics of the electrode and it response as following : internal solution 10-4M , pH (2.5-5) ,temperature (20-30) and response time 2 sec. Calibration response for methyl orange over the concentrationrange 10-3 -10-9 M with R=0.9989 , RSD%=0.1052, D.O.L=0.315X10-9 MEre%=(-0.877- -2.76) , Rec%.=(97.230 -101.711) .
Highlights
The practice of using dyes is perhaps the most ancient art of chemistry
Methyl orange (M.O)were obtained from Fluka, Amitriptylin.HCl standard was obtained from the State Company of Drug Industries and Medical
It was found that the variation in the concentration of the internal solution caused a difference in the potential response and the slope as shown in Table 1.The exact reason for this behavior is not known,but is believed to be due to liquid junction effect
Summary
A thorough literature survey has revealed that no method determination of methyl orange the aim of this work was to develop ion selective electrode for determination methyl orange directly and determination amitriptylin.HCl drug by formation ion-pair on electrode surface
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
