Abstract
Safe, effective alternatives to conventional steroid therapy are lacking in the treatment of ulcerative proctitis and ulcerative proctosigmoiditis. In two identically designed, industry-funded, double-blinded, randomized, placebo-controlled trials, investigators assessed the effectiveness of budesonide foam (2 mg per 25 mL twice daily for 2 weeks, then once daily for 4 weeks) in 546 patients with ulcerative proctitis or ulcerative proctosigmoiditis. At week 6, treatment with budesonide foam …
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