Abstract
For the first time, an injectable bone substitute (IBS) made of a suspension of Calcium phosphate ceramic was used in a clinical trial in human after extraction of non conservable tooth (36 or 46). 11 patients did agree for implantation of their sockets with the biomaterial. It was an explorative study and the results showed no pain due to the biomaterial implantation, no infection, no inflammation and perfect biocompatibility. The safety and the bioactivity of this concept of biomaterial were confirmed in human implantation after several animals’ pre-clinical studies.
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